Minaketan Tripathy
Antimicrobial resistance(AMR) is one of the burning issues that human and animal medicine is dealing with at present. The high percentage of antibiotics those, are discharged from the human or animal body without degradation, is one of the major source of pollution causing unnecessary exposure1.Further human gut and so also the animal rumen microbiota, possibly is hosting the biggest pull of microbial diversity, with extreme complexity and concomitant competition amongst microbial fraternity. Not only the different environment that triggers the evolution and development of microbial resistance but also, the underlying processes that define the community dynamics are yet to be understood and explored. Present developments relating metagenome and other next generation sequencing provide insight regarding the microbial functioning. However, if we look back to look forward, then Understanding the rate at which microbes respire in biological and geochemical systems is central to the development of quantitative descriptions of a broad range of problems in microbiology, from the propagation of disease, attenuation, and to development of resistance2. Respiring microorganisms are similar to mitochondria, in that they employ an electron transport chain to transduce energy from their environment3.Last few years we have been focusing upon newer agents to improve treatment modalities and so also to contain the phenomena of AMR, heavily focussing upon the respiratory path of model organism E.Coli4,5. In this presentation the anti-respiratory activity of Curcumin shall be highlighted using experimental and computational tools to have an insight in to the future possibilities and probabilities regarding AMR.