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Forschungsartikel

Effect of the Pleiotropic Drug CNB-001 on Tissue Plasminogen Activator (tPA) Protease Activity in vitro: Support for Combination Therapy to Treat Acute Ischemic Stroke

Paul A Lapchak and Paul D Boitano

Current state-of-the-art acute ischemic stroke clinical trials are designed to study neuroprotectants when
administered following thrombolysis; tissue plasminogen activat..Mehr sehen»

Fallbericht

A Rare Case of Giant Cell Carcinoma of Lung Presenting with Skin Metastasis

Komal Chaudhary, Govind Singh Rajawat and Suresh Koolwal

Giant Cell Carcinoma of the Lung (GCCL) is a rare histological form of poorly differentiated non-small cell lung cancer, which is classified as a subtype of pulmonary sarcomatoi..Mehr sehen»

Abstrakt

Bio-hybrid of silica nanoparticles and sodium alginate as drug carrier for doxorubicin

Archana Mishra

Mesoporous silica nanoparticles (MSNs) have been widely used as drug carriers [1]. Beneficial characteristic like high surface area, biocompatibility, ease of functionalization ..Mehr sehen»

Forschungsartikel

Novel Techniques in Epilepsy Management: Venous Pacing and Capture of Electrical Activity in the Primate Cortex

Prakriti Gaba BS, Christopher V DeSimone, Benhur D Henz, Paul A Friedman, Charles J Bruce, David R. Holmes, Malini Madhavan, Krithika Vasudevan, Douglas Wahnschaffe, Steven Berhow, Andrew J Danielsen, Dorothy J Ladewig, Susan B Mikell, Susan B Johnson, Scott H Suddendorf, Tomas Kara, Gregory A Worrell and Samuel J Asirvatham

Objective: Pharmacotherapy for epilepsy is limited with 30% of patients’ refractory to this approach of suppressing seizures. Current surgical options are..Mehr sehen»

Zusammenfassung mit Mehrwert

Estimation of CYP3A4*1B single nucleotide polymorphism using target-assembled in-situ detection by synthetic DNA-mounted excimers

Abdul M Gbaj

CYP3A4*1B is a single nucleotide polymorphism of CYP3A4 and is associated with prostate cancer which exhibits higher nifedipine oxidase activity in liver. This research provides..Mehr sehen»

Rezensionsartikel

Increase of Pyramidal Tract Fractional Anisotropy on MRI after Stem Cell Transplantation in ALS Patients

Martínez HR, González-Garza MT, Moreno-Cuevas JE, Caro-Osorio E, Gil-Valadez A, Ocañas CEE, Marioni SS and Hernandez-Torre M

Background and Purpose: Amyotrophic lateral sclerosis (ALS) is characterized by the selective death of motor
neurons. Cortical neuron loss is associated with axonal degen..Mehr sehen»