Anisodowleh Nankali, Farahnaz Keshavarzi, Mina Ataee
"Leiomyosarcoma (LMS) compared to other types of uterine cancers is rare uterine malignancy with a very aggressive course and poor prognosis. We report a confirmed histopathologically uterine leiomyosarcoma by IHC study in virgin woman. Case A: 58-year-old woman was admitted with a history of abdominal enlargement with 4-5 month duration of lower abdominal lump. Tumor marker CA-125 was raised. She underwent hysterectomy, bilateral salpingo-oophorectomy and resection of degenerated leiomyoma’s. Conclusion: The gold standard of uterine leiomyosarcoma treatment is surgery. The prognosis of uterine leiomyosarcoma depends on the extent of disease at the time of diagnosis and the mitotic index in women."